Post by skyship on Jun 12, 2011 1:24:11 GMT -5
Bola Amphiphiles: HOW BOLAAMPHIPHILES ARE MADE!
Bolaamphiphiles Promote Phospholipid Translocation Across Vesicle Membranes
Bolaamphiphiles Promote Phospholipid Translocation Across Vesicle Membranes ... A series of membrane-spanning bolaamphiphiles ... The goal was to determine if the bolaamphiphiles ...
Figure
Phosphatidylcholine-Derived Bolaamphiphiles via Click Chemistry
Edward J. O'Neil, Kristy M. DiVittorio, and Bradley D. Smith
Org. Lett., 2007, 9 (2), pp 199–202
Publication Date (Web): December 14, 2006 (Letter)
DOI: 10.1021/ol062557a
Phosphatidylcholine-Derived Bolaamphiphiles via Click Chemistry ... Bolaamphiphiles ... The chemistry introduces polar 1,4-triazole units into the lipophilic region of the bilayer membrane, and the bolaamphiphiles do not form stable vesicles. ...
Aggregation Behavior of Urocanic Acid Bolaamphiphiles
Juliette Sirieix, Nancy Lauth-de Viguerie, Monique Riviere, and Armand Lattes
Langmuir, 2000, 16 (24), pp 9221–9224
Publication Date (Web): November 3, 2000 (Research Article)
DOI: 10.1021/la000577u
Aggregation Behavior of Urocanic Acid Bolaamphiphiles ... Symmetrical bolaamphiphiles derived from (E) urocanic acid (3-[1H-imidazolyl-(4)-yl]-propenoic acid) were prepared and their self-assembling properties examined. ... In a recent work,20 for three N-alkylated bolaamphiphiles ...
Bolaamphiphiles
Jürgen-Hinrich Fuhrhop and Tianyu Wang
Chem. Rev., 2004, 104 (6), pp 2901–2938
Publication Date (Web): March 12, 2004 (Article)
DOI: 10.1021/cr030602b
Bolaamphiphiles ... Typical scientific subjects were the reactivity and assembly of porphyrins and bolaamphiphiles, spherical and planar monolayer lipid membranes (MLMs), chiral bilayer effects in micellar fibers, long-distance heterodimers, and, most recently, nanowells and the sorting of molecules within them. ... He is currently carrying out postdoctoral research on porphyrin polymers and nanowells made of bolaamphiphiles in t
Figure
Membrane-Mimetic Films of Asymmetric Phosphatidylcholine Lipid Bolaamphiphiles
Xue-Long Sun, Nilanjana Biswas, Toshitsugu Kai, Zhifei Dai, Richard A. Dluhy, and Elliot L. Chaikof
Langmuir, 2006, 22 (3), pp 1201–1208
Publication Date (Web): December 31, 2005 (Research Article)
DOI: 10.1021/la052125t
Membrane-Mimetic Films of Asymmetric Phosphatidylcholine Lipid Bolaamphiphiles ... Membrane-spanning phospholipid bolaamphiphiles ... We have previously reported the synthesis of asymmetric dialkyl phospholipid bolaamphiphiles ...
Polygonal Cylinder Phases of 3-Alkyl-2,5-diphenylthiophene-Based Bolaamphiphiles: Changing Symmetry by Retaining Net Topology
Xiaohong Cheng, Xing Dong, Rong Huang, Xiangbing Zeng, Goran Ungar, Marko Prehm and Carsten Tschierske
Chem. Mater., 2008, 20 (14), pp 4729–4738
Publication Date (Web): June 27, 2008 (Article)
DOI: 10.1021/cm800509u
Polygonal Cylinder Phases of 3-Alkyl-2,5-diphenylthiophene-Based Bolaamphiphiles: Changing Symmetry by Retaining Net Topology ... In the observed phase sequence, the change of the net topology is the same as seen for related linear biphenyl derived bolaamphiphiles, but the symmetry is increased, i.e, rectangular phases are replaced by square lattices. ... (12-15) This concept was successfully applied to two types of T-shape ternary amphiphiles incorporating a rigid rodlike core, namely bolaamphiphiles(12, 15, 16) and facial amphiphiles. ...
Lipid Nanotubes and Microtubes: Experimental Evidence for Unsymmetrical Monolayer Membrane Formation from Unsymmetrical Bolaamphiphiles
Mitsutoshi Masuda and Toshimi Shimizu
Langmuir, 2004, 20 (14), pp 5969–5977
Publication Date (Web): June 02, 2004 (Research Article)
DOI: 10.1021/la049085y
Lipid Nanotubes and Microtubes: Experimental Evidence for Unsymmetrical Monolayer Membrane Formation from Unsymmetrical Bolaamphiphiles ... Unsymmetrical bolaamphiphiles, ω-[N-β-d-glucopyranosylcarbamoyl]alkanoic acids, with even-numbered oligomethylene chains (12, 14, 16, 18, and 20 carbons) self-assembled in water to form lipid nano- and microtubes. ... 8-12 The most direct way to construct an unsymmetrical lipid membrane is to make use of the asymmetry of heteroditopic 1,ω-amphiphiles having headgroups differing in size or properties, that is, “unsymmetrical bolaamphiphiles” .
Dicarboxylic Oligopeptide Bolaamphiphiles: Proton-Triggered Self-Assembly of Microtubes with Loose Solid Surfaces
Masaki Kogiso, Satomi Ohnishi, Kiyoshi Yase, Mitsutoshi Masuda, and Toshimi Shimizu
Langmuir, 1998, 14 (18), pp 4978–4986
Publication Date (Web): July 31, 1998 (Research Article)
DOI: 10.1021/la9802419
Dicarboxylic Oligopeptide Bolaamphiphiles: Proton-Triggered Self-Assembly of Microtubes with Loose Solid Surfaces ... A new family of oligopeptide-based bolaamphiphiles, glycylglycine- (1a−h), glycylglycylglycine- (2a−b), sarcosylsarcosine- (3), l-prolyl-l-proline- (4), glycylsarcosylsarcosine- (5), and glycyl-l-prolyl-l-proline (6)-based bolaamphiphiles with a dicarboxylic headgroup at each end, has been synthesized. ... Self-assembling properties of these bolaamphiphiles ...
Calamitic Bolaamphiphiles with (Semi)Perfluorinated Lateral Chains: Polyphilic Block Molecules with New Liquid Crystalline Phase Structures
Xiaohong Cheng, Marko Prehm, Malay Kumar Das, Jens Kain, Ute Baumeister, Siegmar Diele, Dag Leine, Alfred Blume, and Carsten Tschierske
J. Am. Chem. Soc., 2003, 125 (36), pp 10977–10996
Publication Date (Web): August 14, 2003 (Article)
DOI: 10.1021/ja036213g
Calamitic Bolaamphiphiles with (Semi)Perfluorinated Lateral Chains: Polyphilic Block Molecules with New Liquid Crystalline Phase Structures ... Novel bolaamphiphiles consisting of a rigid biphenyl unit, two terminal polar 1,2-diol units and laterally attached (semi)perfluorinated chains have been synthesized via palladium-catalyzed cross coupling reactions as the key step. ... Rigid bolaamphiphiles with flexible lateral alkyl chains 1/n21 represent one class of compounds in which this approach was very successfully used to obtain novel liquid crystalline phases with complex morphologies. ...
Influence of Flexible Spacers on Liquid-Crystalline Self-Assembly of T-Shaped Bolaamphiphiles
Xiaohong Cheng, Feng Liu, Xiangbing Zeng, Goran Ungar, Jens Kain, Siegmar Diele, Marko Prehm, and Carsten Tschierske
J. Am. Chem. Soc., 2011, 133 (20), pp 7872–7881
Publication Date (Web): May 2, 2011 (Article)
DOI: 10.1021/ja200822z
Influence of Flexible Spacers on Liquid-Crystalline Self-Assembly of T-Shaped Bolaamphiphiles ... T-shaped bolaamphiphiles composed of a biphenyl rigid core, a semiperfluorinated lateral chain, two polar 1,2-diol groups in the terminal positions and flexible alkyl spacers connecting the polar groups with the biphenyl core have been synthesized and investigated by polarizing microscopy, DSC and X-ray scattering. ... It is also shown that introduction of aliphatic spacers in the backbone of the T-shaped bolaamphiphiles replaces the Colrec/c2mm phase made up of rhombic cylinders with the Colsqu/p4mm phase composed of square cylinders. ...
Temperature-Dependent Self-Assembly and Mixing Behavior of Symmetrical Single-Chain Bolaamphiphiles
Annette Meister, Simon Drescher, Vasil M. Garamus, Gran Karlsson, Gesche Graf, Bodo Dobner and Alfred Blume
Langmuir, 2008, 24 (12), pp 6238–6246
Publication Date (Web): May 17, 2008 (Research Article)
DOI: 10.1021/la800166h
Temperature-Dependent Self-Assembly and Mixing Behavior of Symmetrical Single-Chain Bolaamphiphiles ... The temperature-dependent self-assembly and the mixing behavior of symmetrical single-chain bolaamphiphiles with different polymethylene chain lengths and different headgroup structures were investigated in water by differential scanning calorimetry (DSC), cryo transmission electron microscopy (cryo-TEM), and small angle neutron scattering (SANS). ... The odd-numbered analogues were synthesized to study a possible even−odd effect of these bolaamphiphiles ...
Spontaneous Fiber Formation and Hydrogelation of Nucleotide Bolaamphiphiles
Rika Iwaura, Kaname Yoshida, Mitsutoshi Masuda, Kiyoshi Yase, and Toshimi Shimizu
Chem. Mater., 2002, 14 (7), pp 3047–3053
Publication Date (Web): June 13, 2002 (Article)
DOI: 10.1021/cm020263n
Spontaneous Fiber Formation and Hydrogelation of Nucleotide Bolaamphiphiles ... Nucleotide-appended bolaamphiphiles 1−7, in which two 3‘-phosphorylated thymidine moieties are connected to both ends of a long oligomethylene spacer, have been first synthesized. ... Gelation behavior of both bolaamphiphiles strongly depended on the pH and temperature of the aqueous solutions used. ...
Evidence for a Reverse U-Shaped Conformation of Single-Chain Bolaamphiphiles at the Air−Water Interface
Annette Meister, Marcus J. Weygand, Gerald Brezesinski, Andreas Kerth, Simon Drescher, Bodo Dobner, and Alfred Blume
Langmuir, 2007, 23 (11), pp 6063–6069
Publication Date (Web): April 21, 2007 (Research Article)
DOI: 10.1021/la070029h
Evidence for a Reverse U-Shaped Conformation of Single-Chain Bolaamphiphiles at the Air−Water Interface ... Infrared reflection absorption spectroscopy and X-ray reflectivity have been used to elucidate the molecular orientation and hydrocarbon chain conformation and packing of the symmetric long-chain bolaamphiphiles dotriacontane-1,1‘-diyl-bis-[2-(trimethylammonio)ethylphosphate] (PC-C32-PC) and dotriacontane-1,1‘-diyl-bis-[2-(dimethylammonio)ethylphosphate] (Me2PE-C32-Me2PE) at the air−water interface. ... At an area of 0.9−1.1 nm2 per molecule, a surface pressure plateau is reached for both bolaamphiphiles, where the molecules adopt a reverse U-shaped conformation with a strongly tilted alkyl chain. ...
DPDA-10................
Self-Organization of Polymerizable Bolaamphiphiles Bearing Diacetylene Mesogenic Group
Shouchun Yin, Bo Song, Guanqing Liu, Zhiqiang Wang, and Xi Zhang
Langmuir, 2007, 23 (11), pp 5936–5941
Publication Date (Web): April 26, 2007 (Research Article)
DOI: 10.1021/la700281f
Self-Organization of Polymerizable Bolaamphiphiles Bearing Diacetylene Mesogenic Group ... We report herein the synthesis of a series of polymerizable bolaamphiphiles ... The polymerizable bolaamphiphiles are noted as DPDA-n, where n refers to the spacer length of alkyl chain. ...
New Unsymmetrical Bolaamphiphiles: Synthesis, Assembly with DNA, and Application for Gene Delivery
Namrata Jain, Youri Arntz, Valrie Goldschmidt, Guy Duportail, Yves Mly, and Andrey S. Klymchenko
Bioconjugate Chem., 2010, 21 (11), pp 2110–2118
Publication Date (Web): October 14, 2010 (Article)
DOI: 10.1021/bc100334t
New Unsymmetrical Bolaamphiphiles: Synthesis, Assembly with DNA, and Application for Gene Delivery ... In the present work, following new design we synthesized unsymmetrical bolaamphiphiles, molecules bearing neutral sugar (gluconic acid) and dicationic ornithine head groups connected by different long hydrophobic spacers. ... However, bipolar amphiphiles, which are analogues of lipids presenting polar groups at the two opposite sides of the hydrophobic chain(s), so-called bolaamphiphiles (bolas), became the matter of intensive research only in the recent years (1). ...
Stereochemical Effect of Even−Odd Connecting Links on Supramolecular Assemblies Made of 1-Glucosamide Bolaamphiphiles
Toshimi Shimizu and Mitsutoshi Masuda
J. Am. Chem. Soc., 1997, 119 (12), pp 2812–2818
Publication Date (Web): March 26, 1997 (Article)
DOI: 10.1021/ja961226y
Stereochemical Effect of Even−Odd Connecting Links on Supramolecular Assemblies Made of 1-Glucosamide Bolaamphiphiles ... Bolaamphiphiles with a 1-glucosamide-head group at each end, N,N‘-bis(β-d-glucopyranosyl)alkane-1, n-dicarboxamide [Glc-NC(n)CN-Glc, n = 6, 9, 10, 11, 12, 13, and 14], have been synthesized. ... To obtain crystalline fibers stabilized by multiple hydrogen bonds, we have synthesized a series of 1-glucosamide bolaamphiphiles Glc-NC(n)CN-Glc (n = 6, 9, 10, 11, 12, 13, and 14). ...
Novel Galactosylated Polyamine Bolaamphiphiles for Gene Delivery
Karine Fabio, Jérôme Gaucheron, Christophe Di Giorgio, and Pierre Vierling
Bioconjugate Chem., 2003, 14 (2), pp 358–367
Publication Date (Web): February 20, 2003 (Article)
DOI: 10.1021/bc025645y
Novel Galactosylated Polyamine Bolaamphiphiles for Gene Delivery ... We describe the synthesis of a series of α-galacto-ω-polyamine double-chain bolaamphiphiles (Gal-CL) and report on the gene transfer mediated with lipoplexes they form either when used in conjunction with DOPE or with pcTG90:DOPE. ... In continuation of this work, we elaborated novel galacto-polyamine bolaamphiphiles as specific gene transfer agents into ASGP(+) cells, such as hepatocytes. ...
Aqueous Self-Assembly of Unsymmetric Peptide Bolaamphiphiles into Nanofibers with Hydrophilic Cores and Surfaces
Randal C. Claussen, Bryan M. Rabatic, and Samuel I. Stupp
J. Am. Chem. Soc., 2003, 125 (42), pp 12680–12681
Publication Date (Web): September 27, 2003 (Communication)
DOI: 10.1021/ja035882r
Aqueous Self-Assembly of Unsymmetric Peptide Bolaamphiphiles into Nanofibers with Hydrophilic Cores and Surfaces ... Unsymmetric peptide bolaamphiphiles that incorporate (l-glutamyl)3glycine at one terminus and either tetraethylene glycol or aspartic acid at the other were found to form hydrogels at low wt %, presumably by self-assembling into nanofibers presenting (l-glutamyl)3glycine at their surfaces and burying the second headgroup at their cores. ... Bolaamphiphiles ...
Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and l-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes
Tianyu Wang, Jian Jiang, Yu Liu, Zhibo Li, and Minghua Liu
Langmuir, 2010, 26 (24), pp 18694–18700
Publication Date (Web): November 18, 2010 (Article)
DOI: 10.1021/la103435t
Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and l-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes ... Bolaamphiphiles ... At a low pH of 3, bolaamphiphiles formed hydrogels with water and molecules with short and long spacers formed nanofibers and helical nanoribbon−nanotubes, respectively. ...
Coexisting Hydrophobic Compartments through Self-Sorting in Rod-like Micelles of Bisurea Bolaamphiphiles
Asish Pal, S. Karthikeyan and Rint P. Sijbesma
J. Am. Chem. Soc., 2010, 132 (23), pp 7842–7843
Publication Date (Web): May 20, 2010 (Communication)
DOI: 10.1021/ja101872x
Coexisting Hydrophobic Compartments through Self-Sorting in Rod-like Micelles of Bisurea Bolaamphiphiles ... Multiple, coexisting hydrophobic compartments have been created in water using molecular self-sorting among mixtures of bolaamphiphiles ... The selective incorporation of bisurea functionalized fluorescent probes showed that different bolaamphiphiles form separate populations of rod-like micelles, which dynamically coexist in solution, each micelle binding to its correspondingly functionalized guests. ...
tinyurl.com/45378fk
pubs.acs.org/action/doSearch?searchText=%5Ball%3A+How+Bolaamphiphiles+are+made%5D&action=search&type=within&prevSearch=%2528%255Ball%253A%2BHow%2BBolaamphiphiles%2Bare%2Bmade%255D%2529%2BNOT%2B%255Batype%253A%2Bad%255D%2BNOT%2B%255Batype%253A%2Bacs-toc%255D&target=&targetTab=&targetStory=&filter=&startPage=1&func=showSearch&result=true&stemming=&sortBy=&pageSize=20&restrict=&displaySummary=&startYear=&startMonth=&startDay=&endYear=&endMonth=&pubDateRange=&issuetypefield=&author=&includeTOCs=&includeAds=&saveSearchName=&alertme=Never
They are all there.....................
and there is more...................many more...........will wade
through them.
next post. you can see the images.
filaments : Helical ribbons and fibres
spheres
hexagon
group fibers..........Carnicom's images
self assembly solutions form solids...
self assembly helical ribbons
academic.sun.ac.za/unesco/PolymerED2002/Contributions/Naidoo%20A.pdf
Skyship
Bolaamphiphiles Promote Phospholipid Translocation Across Vesicle Membranes
Bolaamphiphiles Promote Phospholipid Translocation Across Vesicle Membranes ... A series of membrane-spanning bolaamphiphiles ... The goal was to determine if the bolaamphiphiles ...
Figure
Phosphatidylcholine-Derived Bolaamphiphiles via Click Chemistry
Edward J. O'Neil, Kristy M. DiVittorio, and Bradley D. Smith
Org. Lett., 2007, 9 (2), pp 199–202
Publication Date (Web): December 14, 2006 (Letter)
DOI: 10.1021/ol062557a
Phosphatidylcholine-Derived Bolaamphiphiles via Click Chemistry ... Bolaamphiphiles ... The chemistry introduces polar 1,4-triazole units into the lipophilic region of the bilayer membrane, and the bolaamphiphiles do not form stable vesicles. ...
Aggregation Behavior of Urocanic Acid Bolaamphiphiles
Juliette Sirieix, Nancy Lauth-de Viguerie, Monique Riviere, and Armand Lattes
Langmuir, 2000, 16 (24), pp 9221–9224
Publication Date (Web): November 3, 2000 (Research Article)
DOI: 10.1021/la000577u
Aggregation Behavior of Urocanic Acid Bolaamphiphiles ... Symmetrical bolaamphiphiles derived from (E) urocanic acid (3-[1H-imidazolyl-(4)-yl]-propenoic acid) were prepared and their self-assembling properties examined. ... In a recent work,20 for three N-alkylated bolaamphiphiles ...
Bolaamphiphiles
Jürgen-Hinrich Fuhrhop and Tianyu Wang
Chem. Rev., 2004, 104 (6), pp 2901–2938
Publication Date (Web): March 12, 2004 (Article)
DOI: 10.1021/cr030602b
Bolaamphiphiles ... Typical scientific subjects were the reactivity and assembly of porphyrins and bolaamphiphiles, spherical and planar monolayer lipid membranes (MLMs), chiral bilayer effects in micellar fibers, long-distance heterodimers, and, most recently, nanowells and the sorting of molecules within them. ... He is currently carrying out postdoctoral research on porphyrin polymers and nanowells made of bolaamphiphiles in t
Figure
Membrane-Mimetic Films of Asymmetric Phosphatidylcholine Lipid Bolaamphiphiles
Xue-Long Sun, Nilanjana Biswas, Toshitsugu Kai, Zhifei Dai, Richard A. Dluhy, and Elliot L. Chaikof
Langmuir, 2006, 22 (3), pp 1201–1208
Publication Date (Web): December 31, 2005 (Research Article)
DOI: 10.1021/la052125t
Membrane-Mimetic Films of Asymmetric Phosphatidylcholine Lipid Bolaamphiphiles ... Membrane-spanning phospholipid bolaamphiphiles ... We have previously reported the synthesis of asymmetric dialkyl phospholipid bolaamphiphiles ...
Polygonal Cylinder Phases of 3-Alkyl-2,5-diphenylthiophene-Based Bolaamphiphiles: Changing Symmetry by Retaining Net Topology
Xiaohong Cheng, Xing Dong, Rong Huang, Xiangbing Zeng, Goran Ungar, Marko Prehm and Carsten Tschierske
Chem. Mater., 2008, 20 (14), pp 4729–4738
Publication Date (Web): June 27, 2008 (Article)
DOI: 10.1021/cm800509u
Polygonal Cylinder Phases of 3-Alkyl-2,5-diphenylthiophene-Based Bolaamphiphiles: Changing Symmetry by Retaining Net Topology ... In the observed phase sequence, the change of the net topology is the same as seen for related linear biphenyl derived bolaamphiphiles, but the symmetry is increased, i.e, rectangular phases are replaced by square lattices. ... (12-15) This concept was successfully applied to two types of T-shape ternary amphiphiles incorporating a rigid rodlike core, namely bolaamphiphiles(12, 15, 16) and facial amphiphiles. ...
Lipid Nanotubes and Microtubes: Experimental Evidence for Unsymmetrical Monolayer Membrane Formation from Unsymmetrical Bolaamphiphiles
Mitsutoshi Masuda and Toshimi Shimizu
Langmuir, 2004, 20 (14), pp 5969–5977
Publication Date (Web): June 02, 2004 (Research Article)
DOI: 10.1021/la049085y
Lipid Nanotubes and Microtubes: Experimental Evidence for Unsymmetrical Monolayer Membrane Formation from Unsymmetrical Bolaamphiphiles ... Unsymmetrical bolaamphiphiles, ω-[N-β-d-glucopyranosylcarbamoyl]alkanoic acids, with even-numbered oligomethylene chains (12, 14, 16, 18, and 20 carbons) self-assembled in water to form lipid nano- and microtubes. ... 8-12 The most direct way to construct an unsymmetrical lipid membrane is to make use of the asymmetry of heteroditopic 1,ω-amphiphiles having headgroups differing in size or properties, that is, “unsymmetrical bolaamphiphiles” .
Dicarboxylic Oligopeptide Bolaamphiphiles: Proton-Triggered Self-Assembly of Microtubes with Loose Solid Surfaces
Masaki Kogiso, Satomi Ohnishi, Kiyoshi Yase, Mitsutoshi Masuda, and Toshimi Shimizu
Langmuir, 1998, 14 (18), pp 4978–4986
Publication Date (Web): July 31, 1998 (Research Article)
DOI: 10.1021/la9802419
Dicarboxylic Oligopeptide Bolaamphiphiles: Proton-Triggered Self-Assembly of Microtubes with Loose Solid Surfaces ... A new family of oligopeptide-based bolaamphiphiles, glycylglycine- (1a−h), glycylglycylglycine- (2a−b), sarcosylsarcosine- (3), l-prolyl-l-proline- (4), glycylsarcosylsarcosine- (5), and glycyl-l-prolyl-l-proline (6)-based bolaamphiphiles with a dicarboxylic headgroup at each end, has been synthesized. ... Self-assembling properties of these bolaamphiphiles ...
Calamitic Bolaamphiphiles with (Semi)Perfluorinated Lateral Chains: Polyphilic Block Molecules with New Liquid Crystalline Phase Structures
Xiaohong Cheng, Marko Prehm, Malay Kumar Das, Jens Kain, Ute Baumeister, Siegmar Diele, Dag Leine, Alfred Blume, and Carsten Tschierske
J. Am. Chem. Soc., 2003, 125 (36), pp 10977–10996
Publication Date (Web): August 14, 2003 (Article)
DOI: 10.1021/ja036213g
Calamitic Bolaamphiphiles with (Semi)Perfluorinated Lateral Chains: Polyphilic Block Molecules with New Liquid Crystalline Phase Structures ... Novel bolaamphiphiles consisting of a rigid biphenyl unit, two terminal polar 1,2-diol units and laterally attached (semi)perfluorinated chains have been synthesized via palladium-catalyzed cross coupling reactions as the key step. ... Rigid bolaamphiphiles with flexible lateral alkyl chains 1/n21 represent one class of compounds in which this approach was very successfully used to obtain novel liquid crystalline phases with complex morphologies. ...
Influence of Flexible Spacers on Liquid-Crystalline Self-Assembly of T-Shaped Bolaamphiphiles
Xiaohong Cheng, Feng Liu, Xiangbing Zeng, Goran Ungar, Jens Kain, Siegmar Diele, Marko Prehm, and Carsten Tschierske
J. Am. Chem. Soc., 2011, 133 (20), pp 7872–7881
Publication Date (Web): May 2, 2011 (Article)
DOI: 10.1021/ja200822z
Influence of Flexible Spacers on Liquid-Crystalline Self-Assembly of T-Shaped Bolaamphiphiles ... T-shaped bolaamphiphiles composed of a biphenyl rigid core, a semiperfluorinated lateral chain, two polar 1,2-diol groups in the terminal positions and flexible alkyl spacers connecting the polar groups with the biphenyl core have been synthesized and investigated by polarizing microscopy, DSC and X-ray scattering. ... It is also shown that introduction of aliphatic spacers in the backbone of the T-shaped bolaamphiphiles replaces the Colrec/c2mm phase made up of rhombic cylinders with the Colsqu/p4mm phase composed of square cylinders. ...
Temperature-Dependent Self-Assembly and Mixing Behavior of Symmetrical Single-Chain Bolaamphiphiles
Annette Meister, Simon Drescher, Vasil M. Garamus, Gran Karlsson, Gesche Graf, Bodo Dobner and Alfred Blume
Langmuir, 2008, 24 (12), pp 6238–6246
Publication Date (Web): May 17, 2008 (Research Article)
DOI: 10.1021/la800166h
Temperature-Dependent Self-Assembly and Mixing Behavior of Symmetrical Single-Chain Bolaamphiphiles ... The temperature-dependent self-assembly and the mixing behavior of symmetrical single-chain bolaamphiphiles with different polymethylene chain lengths and different headgroup structures were investigated in water by differential scanning calorimetry (DSC), cryo transmission electron microscopy (cryo-TEM), and small angle neutron scattering (SANS). ... The odd-numbered analogues were synthesized to study a possible even−odd effect of these bolaamphiphiles ...
Spontaneous Fiber Formation and Hydrogelation of Nucleotide Bolaamphiphiles
Rika Iwaura, Kaname Yoshida, Mitsutoshi Masuda, Kiyoshi Yase, and Toshimi Shimizu
Chem. Mater., 2002, 14 (7), pp 3047–3053
Publication Date (Web): June 13, 2002 (Article)
DOI: 10.1021/cm020263n
Spontaneous Fiber Formation and Hydrogelation of Nucleotide Bolaamphiphiles ... Nucleotide-appended bolaamphiphiles 1−7, in which two 3‘-phosphorylated thymidine moieties are connected to both ends of a long oligomethylene spacer, have been first synthesized. ... Gelation behavior of both bolaamphiphiles strongly depended on the pH and temperature of the aqueous solutions used. ...
Evidence for a Reverse U-Shaped Conformation of Single-Chain Bolaamphiphiles at the Air−Water Interface
Annette Meister, Marcus J. Weygand, Gerald Brezesinski, Andreas Kerth, Simon Drescher, Bodo Dobner, and Alfred Blume
Langmuir, 2007, 23 (11), pp 6063–6069
Publication Date (Web): April 21, 2007 (Research Article)
DOI: 10.1021/la070029h
Evidence for a Reverse U-Shaped Conformation of Single-Chain Bolaamphiphiles at the Air−Water Interface ... Infrared reflection absorption spectroscopy and X-ray reflectivity have been used to elucidate the molecular orientation and hydrocarbon chain conformation and packing of the symmetric long-chain bolaamphiphiles dotriacontane-1,1‘-diyl-bis-[2-(trimethylammonio)ethylphosphate] (PC-C32-PC) and dotriacontane-1,1‘-diyl-bis-[2-(dimethylammonio)ethylphosphate] (Me2PE-C32-Me2PE) at the air−water interface. ... At an area of 0.9−1.1 nm2 per molecule, a surface pressure plateau is reached for both bolaamphiphiles, where the molecules adopt a reverse U-shaped conformation with a strongly tilted alkyl chain. ...
DPDA-10................
Self-Organization of Polymerizable Bolaamphiphiles Bearing Diacetylene Mesogenic Group
Shouchun Yin, Bo Song, Guanqing Liu, Zhiqiang Wang, and Xi Zhang
Langmuir, 2007, 23 (11), pp 5936–5941
Publication Date (Web): April 26, 2007 (Research Article)
DOI: 10.1021/la700281f
Self-Organization of Polymerizable Bolaamphiphiles Bearing Diacetylene Mesogenic Group ... We report herein the synthesis of a series of polymerizable bolaamphiphiles ... The polymerizable bolaamphiphiles are noted as DPDA-n, where n refers to the spacer length of alkyl chain. ...
New Unsymmetrical Bolaamphiphiles: Synthesis, Assembly with DNA, and Application for Gene Delivery
Namrata Jain, Youri Arntz, Valrie Goldschmidt, Guy Duportail, Yves Mly, and Andrey S. Klymchenko
Bioconjugate Chem., 2010, 21 (11), pp 2110–2118
Publication Date (Web): October 14, 2010 (Article)
DOI: 10.1021/bc100334t
New Unsymmetrical Bolaamphiphiles: Synthesis, Assembly with DNA, and Application for Gene Delivery ... In the present work, following new design we synthesized unsymmetrical bolaamphiphiles, molecules bearing neutral sugar (gluconic acid) and dicationic ornithine head groups connected by different long hydrophobic spacers. ... However, bipolar amphiphiles, which are analogues of lipids presenting polar groups at the two opposite sides of the hydrophobic chain(s), so-called bolaamphiphiles (bolas), became the matter of intensive research only in the recent years (1). ...
Stereochemical Effect of Even−Odd Connecting Links on Supramolecular Assemblies Made of 1-Glucosamide Bolaamphiphiles
Toshimi Shimizu and Mitsutoshi Masuda
J. Am. Chem. Soc., 1997, 119 (12), pp 2812–2818
Publication Date (Web): March 26, 1997 (Article)
DOI: 10.1021/ja961226y
Stereochemical Effect of Even−Odd Connecting Links on Supramolecular Assemblies Made of 1-Glucosamide Bolaamphiphiles ... Bolaamphiphiles with a 1-glucosamide-head group at each end, N,N‘-bis(β-d-glucopyranosyl)alkane-1, n-dicarboxamide [Glc-NC(n)CN-Glc, n = 6, 9, 10, 11, 12, 13, and 14], have been synthesized. ... To obtain crystalline fibers stabilized by multiple hydrogen bonds, we have synthesized a series of 1-glucosamide bolaamphiphiles Glc-NC(n)CN-Glc (n = 6, 9, 10, 11, 12, 13, and 14). ...
Novel Galactosylated Polyamine Bolaamphiphiles for Gene Delivery
Karine Fabio, Jérôme Gaucheron, Christophe Di Giorgio, and Pierre Vierling
Bioconjugate Chem., 2003, 14 (2), pp 358–367
Publication Date (Web): February 20, 2003 (Article)
DOI: 10.1021/bc025645y
Novel Galactosylated Polyamine Bolaamphiphiles for Gene Delivery ... We describe the synthesis of a series of α-galacto-ω-polyamine double-chain bolaamphiphiles (Gal-CL) and report on the gene transfer mediated with lipoplexes they form either when used in conjunction with DOPE or with pcTG90:DOPE. ... In continuation of this work, we elaborated novel galacto-polyamine bolaamphiphiles as specific gene transfer agents into ASGP(+) cells, such as hepatocytes. ...
Aqueous Self-Assembly of Unsymmetric Peptide Bolaamphiphiles into Nanofibers with Hydrophilic Cores and Surfaces
Randal C. Claussen, Bryan M. Rabatic, and Samuel I. Stupp
J. Am. Chem. Soc., 2003, 125 (42), pp 12680–12681
Publication Date (Web): September 27, 2003 (Communication)
DOI: 10.1021/ja035882r
Aqueous Self-Assembly of Unsymmetric Peptide Bolaamphiphiles into Nanofibers with Hydrophilic Cores and Surfaces ... Unsymmetric peptide bolaamphiphiles that incorporate (l-glutamyl)3glycine at one terminus and either tetraethylene glycol or aspartic acid at the other were found to form hydrogels at low wt %, presumably by self-assembling into nanofibers presenting (l-glutamyl)3glycine at their surfaces and burying the second headgroup at their cores. ... Bolaamphiphiles ...
Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and l-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes
Tianyu Wang, Jian Jiang, Yu Liu, Zhibo Li, and Minghua Liu
Langmuir, 2010, 26 (24), pp 18694–18700
Publication Date (Web): November 18, 2010 (Article)
DOI: 10.1021/la103435t
Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and l-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes ... Bolaamphiphiles ... At a low pH of 3, bolaamphiphiles formed hydrogels with water and molecules with short and long spacers formed nanofibers and helical nanoribbon−nanotubes, respectively. ...
Coexisting Hydrophobic Compartments through Self-Sorting in Rod-like Micelles of Bisurea Bolaamphiphiles
Asish Pal, S. Karthikeyan and Rint P. Sijbesma
J. Am. Chem. Soc., 2010, 132 (23), pp 7842–7843
Publication Date (Web): May 20, 2010 (Communication)
DOI: 10.1021/ja101872x
Coexisting Hydrophobic Compartments through Self-Sorting in Rod-like Micelles of Bisurea Bolaamphiphiles ... Multiple, coexisting hydrophobic compartments have been created in water using molecular self-sorting among mixtures of bolaamphiphiles ... The selective incorporation of bisurea functionalized fluorescent probes showed that different bolaamphiphiles form separate populations of rod-like micelles, which dynamically coexist in solution, each micelle binding to its correspondingly functionalized guests. ...
tinyurl.com/45378fk
pubs.acs.org/action/doSearch?searchText=%5Ball%3A+How+Bolaamphiphiles+are+made%5D&action=search&type=within&prevSearch=%2528%255Ball%253A%2BHow%2BBolaamphiphiles%2Bare%2Bmade%255D%2529%2BNOT%2B%255Batype%253A%2Bad%255D%2BNOT%2B%255Batype%253A%2Bacs-toc%255D&target=&targetTab=&targetStory=&filter=&startPage=1&func=showSearch&result=true&stemming=&sortBy=&pageSize=20&restrict=&displaySummary=&startYear=&startMonth=&startDay=&endYear=&endMonth=&pubDateRange=&issuetypefield=&author=&includeTOCs=&includeAds=&saveSearchName=&alertme=Never
They are all there.....................
and there is more...................many more...........will wade
through them.
next post. you can see the images.
filaments : Helical ribbons and fibres
spheres
hexagon
group fibers..........Carnicom's images
self assembly solutions form solids...
self assembly helical ribbons
academic.sun.ac.za/unesco/PolymerED2002/Contributions/Naidoo%20A.pdf
Skyship