Post by skyship on Dec 29, 2015 3:38:43 GMT -5
What I mean by this is a protocell: a beginning point to create life:
en.wikipedia.org/wiki/Protocell#From_organic_molecules_to_protocells
again.....this needs to be seen again........
Abstract
This unit describes a straightforward method for preparing glycerol nucleic acid (GNA) phosphoramidite monomers and oligonucleotide polymers using standard cyanoethyl phosphoramidite chemistry. GNA is an unnatural nucleic acid analog composed of an acyclic three-carbon sugar-phosphate backbone that contains one stereogenic center per repeating unit. [/b]GNA has attracted significant attention as a nucleic acid derivative due to its unique ability to form stable Watson-Crick anti-parallel duplex structures with thermal and thermodynamic stabilities rivaling those of natural DNA and RNA. The chemical simplicity of this nucleic acid structure provides access to enantiomerically pure forms of right- and left-handed helical structures that can be used as unnatural building blocks in DNA nanotechnology. Curr. Protoc. Nucleic Acid Chem. 42:4.40.1-4.40.18. © 2010 by John Wiley & Sons, Inc.
Keywords:
glycerol nucleic acid (GNA);phosphoramidite;oligonucleotide;chemical synthesis;solid-phase synthesis;thermal stability;nanotechnology
onlinelibrary.wiley.com/doi/10.1002/0471142700.nc0440s42/abstract
On the primitive Earth, numerous chemical reactions of organic compounds produced the ingredients of life. Of these substances, amphiphilic molecules might be the first player in the evolution from molecular assembly to cellular life.[8][9] A step from vesicle toward protocell might be to develop self-reproducing vesicles coupled with the metabolic system.[10]
Selectivity for compartmentalization[edit]
Self-assembled vesicles are essential components of primitive cells.[1] The second law of thermodynamics requires that the universe move in a direction in which disorder (or entropy) increases, yet life is distinguished by its great degree of organization. Therefore, a boundary is needed to separate life processes from non-living matter.[11] The cell membrane is the only cellular structure that is found in all of the cells of all of the organisms on Earth.[12]
Selectivity for compartmentalization[edit]
Self-assembled vesicles are essential components of primitive cells.[1] The second law of thermodynamics requires that the universe move in a direction in which disorder (or entropy) increases, yet life is distinguished by its great degree of organization. Therefore, a boundary is needed to separate life processes from non-living matter.[11] The cell membrane is the only cellular structure that is found in all of the cells of all of the organisms on Earth.[12]
en.wikipedia.org/wiki/Protocell#From_organic_molecules_to_protocells
again.....this needs to be seen again........
Abstract
This unit describes a straightforward method for preparing glycerol nucleic acid (GNA) phosphoramidite monomers and oligonucleotide polymers using standard cyanoethyl phosphoramidite chemistry. GNA is an unnatural nucleic acid analog composed of an acyclic three-carbon sugar-phosphate backbone that contains one stereogenic center per repeating unit. [/b]GNA has attracted significant attention as a nucleic acid derivative due to its unique ability to form stable Watson-Crick anti-parallel duplex structures with thermal and thermodynamic stabilities rivaling those of natural DNA and RNA. The chemical simplicity of this nucleic acid structure provides access to enantiomerically pure forms of right- and left-handed helical structures that can be used as unnatural building blocks in DNA nanotechnology. Curr. Protoc. Nucleic Acid Chem. 42:4.40.1-4.40.18. © 2010 by John Wiley & Sons, Inc.
Keywords:
glycerol nucleic acid (GNA);phosphoramidite;oligonucleotide;chemical synthesis;solid-phase synthesis;thermal stability;nanotechnology
onlinelibrary.wiley.com/doi/10.1002/0471142700.nc0440s42/abstract