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Post by skyship on Feb 5, 2016 13:43:49 GMT -5
My Morgspine Blog will be closing soon. Please take any or all info for researching. morgspine.bravejournal.com/Most links are available: Here is one that may be beneficial for some researchers. "The growth of the silica structures initiates from nanofibers composed of tiny amorphous particles. Aligned fiber arrays ap- pear to grow from a single or biaxial nanofiber (Fig. 1a), and have a structure similar to a protozoa and its ªflagellumº. The width of the bundle is 300±500 nm. We observe that, after reaching a certain length, the silica fibers in the interior of the bundle cease growth while those in the outer regions continue to grow, forming a cylindrical chamber. Energy dispersive X-ray spectroscopy reveals small crystalline Si nanoparticles"......
Advanced Materials, 2000, 12, No 24, December 15 preview.tinyurl.com/bla27gqActually reference found here: www.nanoscience.gatech.edu/paper/2000/00_AM_2.pdf
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Post by skyship on Feb 5, 2016 13:58:10 GMT -5
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Post by skyship on Feb 5, 2016 16:09:27 GMT -5
The following prediction comes from a digital library we cite for information at ieeexplore.ieee.org. "Recent and future advancements in materials science and nanotechnology could pave the way for the design and development of hybrid morphing probes that literally merge the life sciences with nonliving mechanical devices, thus creating "partially living probes". These hybrid probes would be artificially intelligent and could change shape and perform different functions using smart materials and structures." Sci fi sounding or not...this is our present day and future reality. worldvisionportal.org/wvpforum/viewtopic.php?t=1005
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Post by skyship on Feb 5, 2016 16:11:17 GMT -5
Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. Napierska D1, Thomassen LC, Rabolli V, Lison D, Gonzalez L, Kirsch-Volders M, Martens JA, Hoet PH. Author information Abstract The effect that monodisperse amorphous spherical silica particles of different sizes have on the viability of endothelial cells (EAHY926 cell line) is investigated. The results indicate that exposure to silica nanoparticles causes cytotoxic damage (as indicated by lactate dehydrogenase (LDH) release) and a decrease in cell survival (as determined by the tetrazolium reduction, MTT, assay) in the EAHY926 cell line in a dose-related manner. Concentrations leading to a 50% reduction in cell viability (TC(50)) for the smallest particles tested (14-, 15-, and 16-nm diameter) ranging from 33 to 47 microg cm(-2) of cell culture differ significantly from values assessed for the bigger nanoparticles: 89 and 254 microg cm(-2) (diameter of 19 and 60 nm, respectively). Two fine silica particles with diameters of 104 and 335 nm show very low cytotoxic response compared to nanometer-sized particles with TC(50) values of 1095 and 1087 microg cm(-2), respectively. The smaller particles also appear to affect the exposed cells faster with cell death (by necrosis) being observed within just a few hours. The surface area of the tested particles is an important parameter in determining the toxicity of monodisperse amorphous silica nanoparticles. www.ncbi.nlm.nih.gov/pubmed/19288475
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Post by skyship on Feb 5, 2016 16:12:04 GMT -5
The nanosilica hazard: another variable entity. Napierska D1, Thomassen LC, Lison D, Martens JA, Hoet PH. Author information Abstract Silica nanoparticles (SNPs) are produced on an industrial scale and are an addition to a growing number of commercial products. SNPs also have great potential for a variety of diagnostic and therapeutic applications in medicine. Contrary to the well-studied crystalline micron-sized silica, relatively little information exists on the toxicity of its amorphous and nano-size forms. Because nanoparticles possess novel properties, kinetics and unusual bioactivity, their potential biological effects may differ greatly from those of micron-size bulk materials. In this review, we summarize the physico-chemical properties of the different nano-sized silica materials that can affect their interaction with biological systems, with a specific emphasis on inhalation exposure. We discuss recent in vitro and in vivo investigations into the toxicity of nanosilica, both crystalline and amorphous. Most of the in vitro studies of SNPs report results of cellular uptake, size- and dose-dependent cytotoxicity, increased reactive oxygen species levels and pro-inflammatory stimulation. Evidence from a limited number of in vivo studies demonstrates largely reversible lung inflammation, granuloma formation and focal emphysema, with no progressive lung fibrosis. Clearly, more research with standardized materials is needed to enable comparison of experimental data for the different forms of nanosilicas and to establish which physico-chemical properties are responsible for the observed toxicity of SNPs. www.ncbi.nlm.nih.gov/pubmed/21126379
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Post by skyship on Feb 5, 2016 16:13:02 GMT -5
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Post by skyship on Feb 5, 2016 16:16:12 GMT -5
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