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Post by aqt on Jan 13, 2010 16:48:02 GMT -5
Seems the T3 is the promoter US Patent 7034141 - Packaging of positive-strand RNA virus replicon particles www.patentstorm.us/patents/7034141/claims.html. The recombinant polynucleotide of claim 1, wherein the DNA-dependent RNA polymerase of the first portion is selected from T3, T7, and SP6 DNA-dependent RNA polymerase; wherein the first heterologous promoter is a poxvirus promoter; wherein the at least one psRNAV structural protein of the second portion is an alphavirus structural protein selected from an alphavirus capsid and an alphavirus glycoprotein; and wherein the second heterologous promoter binds to said DNA-dependent RNA polymerase.aqt
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Post by aqt on Jan 13, 2010 16:59:12 GMT -5
and the T3 receptor Thyroid hormone (T3) receptor (T3R) regulates the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) by binding to and activating thyroid hormone response elements (TREs) embedded within the viral NF-kappa B and Sp1 motifs. jvi.asm.org/cgi/content/abstract/69/8/5103retrovirus
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