|
Post by pocoloco on Feb 2, 2010 1:33:07 GMT -5
|
|
|
Post by skyship on Feb 2, 2010 16:30:37 GMT -5
|
|
|
Post by skyship on Feb 2, 2010 17:48:52 GMT -5
3 Kingdoms of Life? of artificial life, the simpler the better for those reconstructing the cell.
Hsp 70 from archaea. From the illuminated light under earths mantle.
Woese knew what he was looking for.
As did others in the field.
Recreating the cell, recreating man, actually making man/woman from the newly integrated reconstructed artificial cell.
Welcome to the machine, however, we are caught in the veil?
Guess what! There are now holes in the Lacy Veil, big holes.
Holes in the Matrix?
Okay, then.
Thank you Mr. Carnicom!
Skyship
|
|
|
Post by lilsissy on Feb 4, 2010 1:01:20 GMT -5
certainly sounds like what I've read of mimi and the kingdoms, mimivirus does not really fit any of the kingdoms.
Jen
|
|
|
Post by skyship on Feb 4, 2010 2:08:33 GMT -5
From Carnicom's link: ,,,,,,,,,,,,, "One of the dominant characteristics of the Archaea is their ability to withstand extreme environmental conditions and stress. It is representative to encounter these forms of life in volcanic vents and deep under the ice shelf; they are prime candidates in the explorations for extraterrestrial life. Many of the organisms from the Archaea group do not require oxygen and can thrive under anaerobic conditions that metabolize carbon dioxide rather than oxygen. Archaea are considered to likely be one of the oldest forms of life on earth. ".......... -------------- That mimi virus since it does not fit in any of the categories, can only be produced in a viral package which would include all three of Woese's categories. Incidently, he is or was involved in the beginning stages of molecular evolution as well. Also, what is interesting is that the archaea is involved in the heat shock proteins, and the cold shock proteins, so we know it came from archaea which are extremophiles. They named on of the smaller virues inside the mimi virus as Sputnik virus, the russian space ship. why? en.wikipedia.org/wiki/Sputnik_1================= Seems they want us to believe this is coming from outer space, aliens. when they created the aliens, the alien foreign adaptation package, or mutation, since viruses have the power to mute into genes, something called substance P seems important in this construction. related to aromatic hyrdrocarbons. polystyrene? ==================== Janus particle: wonder what it is made of? ------------------- Summary A paradox for cancer biology is represented by the fact that some oncogenes, including c-myc, provide an advantage to cancer cells by stimulating uncontrolled proliferation while, at the same time, they exert a pro-apoptotic activity. The prominent roles of c-myc and the relevance of phosphorylation and subcellular compartmentalization of c-Myc protein are described in this review, which focuses also the possible strategies to modulate (i.e. up- and down-regulate) the c-myc level. The gene expression targeted approach of c-myc modulation as anticancer therapeutic treatment is discussed." ...."c-myc initiates a transcriptional program that controls hundred of genes belonging to different functional categories of myc targets. Some of them can be considered as direct targets, others are indirectly regulated. The investigation of the nature of the interaction among c-Myc network members revealed that it could be modulated through the formation of distinct sub-nuclear structures localized in specific compartments (Yin et al, 2001). Figure 1. Representation of the oncogene c-myc as the double-headed Janus deity. Looking in the direction of both cell proliferation and death, c-myc controls the basic life processes. ======================= So, Janus particle is what? controls the life processes? the c-myc? ====================== www.gtmb.org/VOL8A/GTMBVOL8AHTML/35_Supino/35_Supino-Scovassi_385-394.htm
|
|
|
Post by skyship on Feb 4, 2010 2:28:19 GMT -5
Myc (cMyc) codes for a protein that binds to the DNA of other genes and is therefore a transcription factor. When a gene like Myc is altered to cause cancer, the cancerous version of the gene is called an oncogene. The healthy version of the gene that it is derived from is called a proto-oncogene. Myc gene encodes for a transcription factor that is believed to regulate expression of 15% of all genes [1] through binding on Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferases (HATs). Myc belongs to Myc family of transcription factors, which also includes N-Myc and L-Myc genes. Myc-family transcription factors contain the bHLH/LZ (basic Helix-Loop-Helix Leucine Zipper) domain. en.wikipedia.org/wiki/Myc===================== Janus particle: mmmm Ras/Raf/MAPK and Janus protein tyrosine kinases (JAKs)/Stat3 cascades are two major signaling pathways of growth factors and cytokines so janus protein tyrosine kinases jaks? ----- Just another kinase? or use of Janus Particle? There are four JAK family members: * Janus kinase 1 (JAK1) * Janus kinase 2 (JAK2) * Janus kinase 3 (JAK3) * Tyrosine kinase 2 (TYK2) en.wikipedia.org/wiki/Janus_kinaseskyship
|
|
|
Post by skyship on Feb 4, 2010 3:42:39 GMT -5
|
|
|
Post by skyship on Feb 4, 2010 10:40:32 GMT -5
|
|
|
Post by aqt on Feb 4, 2010 16:53:47 GMT -5
PAH's POLY aromatic hydrocarbons POLYstyrene POLYethyline POLYvinyl POLY-ESTER POLYbutune POLYisoprene POLYvinylpyrrolidone en.wikipedia.org/wiki/PolyvinylpyrrolidoneOther references state that polyvinyl pyrrolidone and its derivatives are fully from mineral synthetic origin aqt
|
|
|
Post by aqt on Feb 4, 2010 16:56:49 GMT -5
Human body implant of graphitic carbon fiber reinforced ultra-high molecular weight polyethylene www.freepatentsonline.com/4055862.htmlThe present invention is based on the discoveries that ultra-high molecular weight polyethylene can be fabricated into highly useful human body implants by
|
|
|
Post by aqt on Feb 4, 2010 17:01:03 GMT -5
|
|
|
Post by skyship on Feb 4, 2010 23:26:25 GMT -5
I do think there is silica in there as well. So if there is a mix of poly ethylene glycol and silica. there could be the connection or chemical reaction that would cause this new construction out of those two to become a moving 3 chemical reaction. If that makes sense, that then mimicks and forms a brand new axon. etc.
mmmmmmmmmm seems Si04 was the silica that forms. mmm
will look more into that.
skyship
|
|
|
Post by aqt on Feb 5, 2010 17:04:46 GMT -5
pubs.acs.org/doi/abs/10.1021/ja0653167Polyethylene (PE) and silica are perhaps the simplest and most common organic and inorganic polymers, respectively. We describe, for the first time, a physically interpenetrating nanocomposite between these two elementary polymerslooks like our "egg-like" structures, no? FUSING ORGANIC AND INORGANIC POLYMERSaqt
|
|
|
Post by aqt on Feb 5, 2010 17:15:37 GMT -5
|
|
|
Post by aqt on Feb 5, 2010 17:18:00 GMT -5
Abstract Monolayer films of n-propyl trichlorosilane (PTS) self-assembled on glass substrates were investigated using Fourier transform infrared spectroscopy (FTIR) and planar array infrared spectroscopic imaging (PA-IR spectroscopic imaging) as a function of three different solvents (hexane, benzene and toluene). tiny.cc/WkMhZaqt
|
|
|
Post by aqt on Feb 5, 2010 17:22:18 GMT -5
Enhanced blood compatibility of silicon coated with a self-assembled poly(ethylene glycol) and monomethoxypoly(ethylene glycol) cat.inist.fr/?aModele=afficheN&cpsidt=2287111Silicon biomedical microdevices generally require surface modifications to improve their biocompatibility. One of the challenges in the field is the development of molecular coatings for devices with nanofeatures. In this paper we report the results of our investigation of synthetic poly(ethylene glycol) (PEG) and monomethoxypoly(ethylene glycol) (MPEG) coatings incorporating functional groups that in turn immobilize self-assembled (SA) monolayers. The properties of the modified surfaces were characterized by ellipsometry and scanning electron microscopy (SEM). Protein adsorption as well as platelet adhesion to the treated surfaces were studied to evaluate the non-fouling property of the PEG-enriched surface layers. Both PEG- and MPEG-modified surfaces showed significant suppression in plasma protein adsorption and platelet adhesion.
|
|
|
Post by aqt on Feb 5, 2010 17:28:00 GMT -5
Self-assembly approach toward magnetic silica-type nanoparticles of different shapes from reverse block copolymer mesophases The hybrid mesophases with sphere, cylinder, and lamellar morphologies containing the inorganic components in the minority phases are characterized through a combination of small-angle X-ray scattering (SAXS), transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM), and electron energy loss spectroscopy (EELS). The results pave the way to functional, i.e., magnetic nanoparticles where the size, shape, and iron oxide concentration can be controlled opening a range of possible applications. www.ncbi.nlm.nih.gov/pubmed/14582998
|
|
|
Post by aqt on Feb 5, 2010 17:29:29 GMT -5
|
|
|
Post by aqt on Feb 6, 2010 16:46:59 GMT -5
so, they figured out that the nanoparticles could be excreted through the renal system... More interestingly, in vivo real-time imaged dominant signal in bladder and urine excretion studies revealed that all three types of iv-injected SiNPs with a size of ¡45 nm were partly excreted through the renal excretion route. These conclusions were further confirmed through ex vivo organ optical imaging and TEM imaging and energy-dispersed X-ray spectrum analysis of urine samples. cat.inist.fr/?aModele=afficheN&cpsidt=20955389These findings would have direct implications for the use of SiNPs as delivery systems and imaging tools in live animals. Furthermore, our results demonstrate that the in vivo optical imaging method is helpful for in vivo sensing the biological effects of SiNPs by using luminescent dye doped in the silica matrix as a synchronous signal
|
|
|
Post by aqt on Feb 6, 2010 16:52:19 GMT -5
Protein Micropatterning via Self-Assembly of Nanoparticles Micropatterning of proteins on non-planar surfaces is achieved by immobilization of proteins on silica nanoparticles and self-assembly of the nanoparticles in patterned microwells. The atomic force microscopy (Figure, left, 3 m × 3 m) and fluorescence (right) images of protein-coated silica nanoparticles in microwells confirm the viability of this process. www3.interscience.wiley.com/journal/109876323/abstract?CRETRY=1&SRETRY=0
|
|
|
Post by aqt on Feb 6, 2010 16:54:33 GMT -5
perhaps the fibers enter us...transparent/clear/white perhaps they change color depending on which protein is micropatterned..?? possible? perhaps they are silica/silicone/PEG protein coated silica nanoparticles???If they are coated in proteins, our Immunne systems will not recognize the silica nanoparticle as an invader and will do nothing to attempt to stop it. above they had already fused together the organic/inorganic polymers was this the base?....the "polymers"...creating "fibers".. humph. aqt
|
|
|
Post by lilsissy on Feb 7, 2010 3:50:53 GMT -5
aqt said, perhaps they change color depending on which protein is micropatterned..?? possible?
Probable, I have read of this very happening. Jen
|
|
|
Post by aqt on Feb 8, 2010 17:08:05 GMT -5
Scientists in Maryland have already built the world's first entirely handcrafted chromosome -- a large looping strand of DNA made from scratch in a laboratory, containing all the instructions a microbe needs to live and reproduce. In the coming year, they hope to transplant it into a cell, where it is expected to "boot itself up," like software downloaded from the Internet, and cajole the waiting cell to do its bidding. And while the first synthetic chromosome is a plagiarized version of a natural one, others that code for life forms that have never existed before are already under construction. The cobbling together of life from synthetic DNA, scientists and philosophers agree, will be a watershed event, blurring the line between biological and artificial -- and forcing a rethinking of what it means for a thing to be alive. www.washingtonpost.com/wp-dyn/content/article/2007/12/16/AR2007121601900.html
|
|
|
Post by aqt on Feb 8, 2010 17:13:21 GMT -5
|
|
|
Post by aqt on Feb 8, 2010 17:15:57 GMT -5
|
|
|
Post by aqt on Feb 8, 2010 17:20:58 GMT -5
|
|
|
Post by aqt on Feb 8, 2010 17:23:16 GMT -5
|
|
|
Post by aqt on Feb 8, 2010 17:27:11 GMT -5
|
|
|
Post by aqt on Feb 8, 2010 17:29:03 GMT -5
Fusion genes and proteins can also be made in the laboratory by combining genes or parts of genes from the same or different organisms. www.cancer.gov/dictionary/?CdrID=44591cancer.gov? appropriate. aqt
|
|
|
Post by aqt on Feb 8, 2010 17:31:18 GMT -5
fusion protein purification www.cancer.gov/dictionary/?CdrID=44591seems it has to do with removing the metals or "chelating" that are in organism after fusion...nickel and cobalt...cobalt60? are we getting somewhere here? LOL aqt
|
|