jill
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Post by jill on Jun 3, 2009 12:26:29 GMT -5
Lots out there on the subject. Back in 2007- I had posted on a now dead board about Nanocytes.
Topic: Nanocytes (Read 68 times) Jill Guest
Nanocytes « Thread Started on Apr 15, 2007, 7:19pm »
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jill
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Post by jill on Jun 3, 2009 12:28:20 GMT -5
www.igb.fraunhofer.de/www/GF/Biomaterialien/en/GFBM_27_Nanocytes.en.htmlNanocytes® – Cell-mimetic nanoparticles Silica nanoparticles Silica nanoparticles, scanning electron microscopic image. Active principle of nanocytes Active principle of Nanocytes®. Silica nanoparticles are functionalized with a cytokine (TNF) and induce the specific cell response by binding to the target cell receptor. Like "cellular foreign ministers", membrane-bound proteins govern the interactions of the cell with its environment. They thus hold important key positions and are accordingly very popular among research scientists – at least in theory, because in practice these active membrane proteins are difficult to control. Ultimately, they often have complex structures and exert their biological activity only in certain spatial conformations and arrangements. At the Fraunhofer IGB, therefore, hybrid biological and synthetic particles have been developed which simulate the properties at the cell surfaces. On the surface of these cell-mimetic, i.e. cell-imitating, nanoparticles, membrane proteins are bound in such a way that their biological properties are fully maintained. The basis of these so-called Nanocytes® is constituted by chemically customized nanoparticles which are created either from silicon oxide and other inorganic materials or from different organic polymers. The surface of the tiny particles can be modified according to their use so that different biomolecules can be bound to them. With the hybrid particles, research scientists at the Fraunhofer IGB have created a variable building block system which can be used as a qualitatively new tool in cell biological or immunological research and in diagnostic systems. Nanocytes® can also be used in medical technology as a component of composite membranes. Nanocytes_cell death_22min Nanocytes-cell death_40min Nanocytes® (marked in red) link up with a target cell (with proteins marked in green inside the cell) and trigger programmed cell death. Top: after 20 minutes. Bottom: after 40 minutes. Cytokine-functionalized Nanocytes® – a future prospect for cancer therapy Anyone with cancer not only has to suffer from the disease, but also from surgery, chemotherapy and radiation with their sometimes severe side-effects. No wonder that intensive work is being undertaken on gentler treatment alternatives. One source of hope is to be found in the cytokines of tumour necrosis factors (TNF). These membrane-bound signal proteins induce programmed cell death (apoptosis) in tumor cells. In co-operation with the Institute for Cell Biology and Immunology of the University of Stuttgart (Prof. Klaus Pfizenmaier), bio-active cytokine (TNF) has been coupled to silica particles. The resultant Nanocytes® cause suicidal reactions in cultured human cells, which otherwise are known only with membrane-bound cytokines. Cytokine-functionalized Nanocytes® thus open the way to entirely new experimental approaches in immunological and cell biological research, as well as in the development of diagnostic procedures. For therapeutic use, Nanocytes® would also have to be provided with a biological target function in addition to the cytokine. As a result of this detection function, cytokine Nanocytes® could then one day journey through the human body, identify cancer cells among thousands upon thousands of body cells, bind to them and trigger targeted self-destruction.
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jill
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Post by jill on Jun 3, 2009 12:31:53 GMT -5
Another Fraunhofer patent: www.faqs.org/patents/inv/194930Wolfgang Fraunhofer NEWTON, MA US 1. 20080292642 Crystalline anti-human IL-12 antibodies - batch crystallization methods for crystallizing an anti-hIL-12 antibody that allows the production of the 11-27-2008
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Post by aqt on Jun 3, 2009 13:13:30 GMT -5
Tovar and his colleagues at Stuttgart University have developed bio-functional nanoparticles. Known as nanocytes®, these carry TNF proteins on their surface. www.physorg.com/news10962.htmlNanocytes® consist of a silicate ... so, which is it? Cyanobacterial daughter cells or a highly developed bio-functional nano-particle? 2 entities with the same name....talk about confusing!! aqt
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Post by aqt on Jun 3, 2009 13:19:22 GMT -5
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Post by skyship on Jun 3, 2009 21:19:26 GMT -5
nanocytes, I bet are used for bioremediation. Could have been in pond. also are used to kill TNF cells. It is the TNF we need to look at, seems the nanocytes are used to recognize the TNF. seems Tumor Necrosis Factor was used as immunity to the malaria parasite. so, then one now has the malaria parasite and the tumor necrosis factor going on. A small proportion of individuals infected with Plasmodium falciparum develop cerebral malaria. Why it affects some infected individuals but not others is poorly understood. Since tumor necrosis factor (TNF) has been implicated strongly in the pathogenesis of cerebral malaria, here we have compared different parasite isolates for their ability to induce TNF production by human mononuclear cells in vitro. Wild isolates were collected from 34 Gambian children with cerebral malaria and 66 children with uncomplicated malaria fever. Cerebral malaria isolates tended to stimulate more TNF production than mild malaria isolates, hut there was considerable overlap between the two groups, and the present data provide only limited support for the hypothesis that cerebral malaria is caused by strains of P. falciparum inducing high levels of TNF. However, it is notable that the amounts of TNF induced by different wild isolates from a single locality differed by over 100-fold. The biological significance of this polymorphism deserves further scrutiny in view of the central role that TNF is believed to play in host defense and in the clinical symptomatology of human malaria. Polymorphism and TNF............... cat.inist.fr/?aModele=afficheN&cpsidt=3485219cerebral malaria tinyurl.com/pcfjqbwww.dana.org/news/cerebrum/detail.aspx?id=7858TNF seems to happen with other parasites as well: more related to trypanasoma as well: TNF makes parasites grow? Trypanosomes are highly sensitive to TNF-a, reactive oxygen and nitrogen intermediates. TNF-a is also involved in cachexia. IFN-g acts as a parasite growth factor. AQT, you mentioned mimicry: here from the trypanasoma, wonder if they tried to use as a biospray? forcing the TNF? www.scielo.br/scielo.php?pid=S0001-37652006000400004&script=sci_arttextnote the mimicry and how the TNF causes more problems. mimic our tissues? Skyship
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jill
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Post by jill on Jun 4, 2009 6:06:33 GMT -5
Confusing it is, AQT, but somewhere in the Nanocytes is the key to what Tam Tam had been talking about all along (2005 onward).
It irritates me that I shelved that info- forgot about it until recently.
The sentence in the post above had been repeated frequently by Tam Tam, along with:
Why did previous investigators not find well defined mitochondria? "I am convinced that these Mitochondria are from Human Cells (Karvita B Ahuwalia, 2001)"
When Tam Tam first started posting on the Biology Board, he mentioned something 'Novel'- Prototheca=Mesomycetozoea
He went on to state the new vs old terminology- New being the Mesomycetozoa- the old being Rhinosporidium seeberi, which WAS classified as a fungus- and now a novel clade of aquatic protistan parasites.
****** Identification of a unicellular, non-pigmented alga that mediates growth inhibition in anuran tadpoles: a new species of the genus Prototheca (Chlorophyceae: Chlorococcales) ****** Mitochondrial genes in the colourless alga Prototheca wickerhamii resemble plant genes in their exons but fungal genes in their introns.
Sky, you could well be correct that the Nanocytes are used for Bio-remediation and may have been in the pond.
Tam Tam posts (the Dr's question) as to why investigators did not find well defined mitochondria (human cells) in that pond. That and the various uses for the Nanocytes seem to hold those answers.
I will see what more I can learn about the Nanocytes....
Jill
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jill
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Post by jill on Jun 4, 2009 8:29:33 GMT -5
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jill
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Post by jill on Jun 4, 2009 10:07:29 GMT -5
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jill
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Post by jill on Jun 4, 2009 10:34:30 GMT -5
nanotechwire.com/news.asp?nid=2933&ntid=130&pg=14 2/16/2006 1:53:33 AM German researchers design hybrid bio-synthetic nanoparticles to fight cancer Fair use Excerpt: They are only a few nanometers in size, but their impact is tremendous: The tiny particles drive cancer cells to their death in no time at all. At nano tech 2006 in Japan from Feb. 21-23 researchers from the German Fraunhofer-Gesellschaft will demonstrate in Hall 4 the great efficiency of nanoscopic particles as a vehicle for drug delivery. end excerpts Nanocytes
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Post by skyship on Jun 4, 2009 13:06:05 GMT -5
Jill, I am wondering about the dsDNA and this retroviral. Seems they have revived old viruses. Why did previous investigators not find well defined mitochondria? "I am convinced that these Mitochondria are from Human Cells (Karvita B Ahuwalia, 2001)" now this crithidia luciliae name wise would revive the LUCA the last universal common ancestor Lucy? did she die from this? This is the protozoan that is in trypanasoma, those forms I am pulling out. They seem to attach one to another. They have about eight stages. However, this is used in the dsDNA seems they made antibodies to it, made from it. But, it is a parasite, they use to diagnose SLE. seems there is a connection between old viruses that are carried by this: crithitia: oh my seems to solve the bee problem? Crithidia bombi is perhaps the most well documented species and is a parasite of bumblebees. Other species include C. fasciculata, C. deanei, C. desouzai, C. oncopelti, C. guilhermei and C. luciliae. C. deanei is atypical of the Crithidia genus, and it has been argued not a member of the Crithidia at all. It is also not typical of trypanosomatids because of its unusual shape and it harbours endosymbiotic bacteria.[2] These parasites may be at least partially responsible for colony collapse in wild bee populations. They cause the bees to lose their ability to distinguish between flowers that contain nectar and those that don't. They make many mistakes by visiting nectar scarce flowers and in so doing, slowly starve to death. Commercially bred bees are used in greenhouses, to pollinate, for example, tomatoes and these bees typically harbor this parasite, while wild bees do not. It is believed that the commercial bees transmitted the parasite to wild populations in some cases. They escape from the greenhouses through vents and a simple mesh could help prevent their escape. en.wikipedia.org/wiki/CrithidiaI have been looking for the protozoan. and this one seems to be similar to what we have, however, I believe was used as dsDNA with it's virion, which is an old one. I believe they constructed this from the array of the crithidia and put in wild. They also tried to genetically engineer the reduviid bug that carries this. However, I believe is in all insects now. It is not the standard Chagas' disease protozoan, is a chimera. more on this later will start a link on the protozoan and see if we can weed out its construction. skyship Here is a phot of it. I found something yesterday that said this type thing is in tomatoes. So, genetically modified tomatoes, ? I know the HSP 70 is in the tomato. oh my used against native DNA............holy moloney............ A genus, the trypanosomes, in the family Trypanosomatidae found in arthropods and other invertebrates. * C. luciliae — commercial preparations of this organism are used as substrate in assays for serum antibodies against native DNA. Woooooooooooooo trypanothione synthase ,,,,,,, the synthesis................is this it? getting inside here: In enzymology, a trypanothione synthase (EC 6.3.1.9) is an enzyme that catalyzes the chemical reaction glutathione + glutathionylspermidine + ATP \rightleftharpoons N1,N8-bis(glutathionyl)spermidine + ADP + phosphate The 3 substrates of this enzyme are glutathione, glutathionylspermidine, and ATP, whereas its 3 products are N1,N8-bis(glutathionyl)spermidine, ADP, and phosphate. This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is glutathionylspermidine:glutathione ligase (ADP-forming). www.answers.com/topic/trypanothione-synthasenow wonder how this relates to Mitochondria? so if we type in mitochondria and trypanothione-synthase? more later. skyship
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Post by skyship on Jun 4, 2009 13:08:47 GMT -5
I do not want to take from the nanocytes, so will start new thread just on this. However, wonder if the nanocytes consist of this? Nanocytes mention on page 4 here, type of phytoplankton, www.scribd.com/doc/7076383/PhytoplanktonsI know the UN introduced some man made plankton into fisheries years back to change the fisheries and make them adapt to using this phytoplankton, because the other phytoplankton that is usually in the waters has disappeared. Most likely due to to introduction of this new plankton. A novel created plankton. could be related to the nanocytes. One could make a directed evolution take place. Evolutionists know they can speed up the spontaneous generation of other formed species, if they make the intermediary work. the missing links to make evolution happen! dwarf cells (nanocytes)? more later skyship
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Post by skyship on Jun 4, 2009 13:25:31 GMT -5
Nanocyte INC.? Imagine a farm in the ocean, where cowboys corral sea life instead of livestock. While there is not yet talk of a jellyfish stampede, a team of Israeli scientists have taken a natural mechanism in sea animals used for 700 million years and have turned it into a medical advance that could make injections pain-free. Researchers at NanoCyte startup have discovered a way to take the miniscule stingers found in sea creatures and fill them with important pharmaceuticals that can be delivered painlessly through the skin of a patient. A person simply rubs on a cream loaded with sea-life stingers and embedded with a drug such as insulin onto the skin, activating the stingers which inject the drug. In the near future, this may mean no more daily injections for diabetics, no more injections at the dentist office and no more injections before surgery. Anyone who has been stung by a jellyfish knows how fast the pain can travel. Based on this mechanism, NanoCyte investigated non-toxic versions of similar animals, the sea anemone, and discovered a way to put its sting to good use. Sea anenomes may look like flowers, but they are a boneless animal which prey on other sea life. They live in the sea usually attached to the sea bed or rock, but can move around slowly. scroll about half way down note picture, sea anemone? or jelly fish? Jellyfish that can get under your skin jmcarroll-marinebio.blogspot.com/2006_05_01_archive.html
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jill
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Post by jill on Jun 4, 2009 13:52:09 GMT -5
Sky, I took a look at the Crithidia you mention- wow- that is one deep subject! While many of the clues from Tam Tam as well as yourself, lead to Trypanosome- I so hope that is the wrong path. No cure- I read in the Wiki- about the Colony collapse- in wild bees as relates to the Crithidia - just as you mention... Heaven help us. en.wikipedia.org/wiki/CrithidiaExcerpt: These parasites may be at least partially responsible for colony collapse in wild bee populations. They cause the bees to lose their ability to distinguish between flowers that contain nectar and those that don't. They make many mistakes by visiting nectar scarce flowers and in so doing, slowly starve to death. Commercially bred bees are used in greenhouses, to pollinate, for example, tomatoes and these bees typically harbor this parasite, while wild bees do not. It is believed that the commercial bees transmitted the parasite to wild populations in some cases. They escape from the greenhouses through vents and a simple mesh could help prevent their escape. end So it would seem that with a little more care, these commercially bred bees could be contained? Simple mesh? www.thebindingsite.com/crithidia-23.aspwww.thebindingsite.com/images/crithidia.jpg Check this out, Sky: lyme-fiber-disease.proboards.com/index.cgi?board=fromhereandthere&action=display&thread=725&page=2www.protomag.com/assets/natures-designFair use Excerpt: MICRO STINGS Sea anemones, along with other members of the phylum Cnidaria, which includes corals and jellyfish, have evolved highly efficient means to capture prey and deter predators. Their feeding tentacles have specialized stinging cells called nematocytes that contain microcapsules called nematocysts. When they detect the presence of food or foe, the nematocysts fire harpoonlike hollow threads through which the anemone pumps a cocktail of deadly toxins. NanoCyte, a biotech startup in Zemach, Israel, is extracting microcapsules from the cells of sea anemones (which are nontoxic to humans) to create a topical-drug delivery device. Each microcapsule is dehydrated into a sterile powder and immersed in a gel, but remains intact. A patient must first apply the gel, then the drug itself in liquid form. The drug rehydrates the microcapsules, then the pressure of osmosis forces the hollow, barbed thread coiled in the microcapsule through the skin. Once the drug has been pumped into the patient, the threads degrade in the skin. And because only minuscule quantities of an active pharmaceutical ingredient penetrate the skin, the risk of side effects is low.
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jill
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Post by jill on Jun 4, 2009 14:23:20 GMT -5
Sky,
That link you posted with the Jellyfish? That is very interesting, isn't it?
This Nanocyte Inc is matching most of Tam Tams' clues from years ago.
Recall - Tam Tam said:
"This organism (target) was created for experimentation regarding artificial skin, wound dressing, cancer study, with obvious spin off's into the medical, military and commercial markets. From what I have gathered it was an unintentional release. However those of who you speak have taken advantage of this release with what seems to be LONG TERM SUPPRESSIVE THERAPY as an end goal. "
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Post by aqt on Jun 4, 2009 14:35:23 GMT -5
Ladies, let's not forget the chemtrails
nanocytes could be sprayed from planes....ending up in ponds ect..
keep up the great work....will work more on this tomorrow
you girls are the bestest!!!!!
Thanks for your contributions!!!!
aqt
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jill
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Post by jill on Jun 4, 2009 15:38:09 GMT -5
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Post by skyship on Jun 4, 2009 16:06:38 GMT -5
it is topical, so could be sprayed in air. as a defense against Chagas, a new reformed type? seems to fit. so if the protozoan is the crithidia by way of nanocyte, then the capsules would be in the nanotube like nanocyte. wooooooooo ties us right into Fraunhofer and the TNF. www.nanowerk.com/news/newsid=276.phpwll forget the buckyballs just spray the particles...................... However, seems the TNF is causing SLE. what is interesting is that this seems related to both Downs syndrome and Alzheimers. and the pancreas. Trypanasoma like causes mega colon, swelling by eyes, mega esophogus and myrocardial infarctions, or enlarged heart. but if related to SLE, there is the sclerosing. skyship
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Post by skyship on Jun 4, 2009 19:54:24 GMT -5
jjill, Here is a connection to not only p. aeruginosa and nanocytes but b. subtilis to clean up that. I believe this is the same scientist who discovered the "mitochondrian link' Ahluwalia, K. B., N. Maheshwari, et al. (1997). "Rhinosporidiosis: a study that resolves etiologic controversies." Am J Rhinol 11(6): 479-83. We have been able to isolate the cyanobacterium Microcystis aeruginosa from water samples of ponds and river where patients of rhinosporidiosis were bathing. It is likely that this cyanobacterium is the causative agents of this disease. The bluish-green cells of M. aeruginosa also have a colorless small cell stage called nanocyte which has been detected in clear waters of all the pond and river samples studied. Both large cells and nanocytes of M. aeruginosa could be recognized inside the round bodies of rhinosporidiosis by light and electron microscopy. Further work on culturing this organism from excised samples and evaluation for drug therapy are in progress. It is hoped that, if therapy becomes available, no surgery would be required for this disease. It is suggested that the waters from ponds and lakes, as well as municipal and recreational waters, be checked for the nanocyte stage of M. aeruginosa. Etiological controversies of rhinosporidiosis have been reasonably solved. The new findings justify a change in the name "rhinosporidiosis" that had been associated with the fungus Rhinosporidium Seeberi. Ahn, C. Y., S. H. Joung, et al. (2003). "Selective control of cyanobacteria by surfactin-containing culture broth of Bacillus subtilis C1." Biotechnol Lett 25(14): 1137-42. Of several types of chemical surfactants and biosurfactants, only the culture broth of Bacillus subtilis C1 containing surfactin at 10 mg l(-1) completely inhibited the growth of Microcystis aeruginosa, a bloom-forming cyanobacterium in highly eutrophic lakes. The broth with 10 mg surfactin l(-1) also removed 85% of the maximally grown M. aeruginosa (chlorophyll-a concentration, 1000 microg l(-1)) within 2 d, and the removal efficiency was enhanced by Ca2+ over 1 mM. The growth of Anabaena affinis, another bloom-forming cyanobacterium, was also inhibited about 70% with surfactin at 10 mg l(-1) broth. However, the effect of the broth was delayed over 3 d in the green algae, Chlorella vulgaris and Scenedesmus sp., and was negligible in a diatom, Navicula sp., indicating the potential for the selective control of cyanobacterial blooms.oehha.ca.gov/ecotox/Microcystin.htmlremember the p. putida that formed from the p. aeruginosa? grady's assumption those were from silica spheres. used in water remediation as well. Roberta Louise had p. aeruginosa pneumonia at one time, she suffered so badly, it must be all over New Zeeland. so if the nanocytes are colorless in the small stage, then the tranparent like things we see mmmmmmm skyship
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Post by aqt on Jun 5, 2009 5:53:13 GMT -5
God Bless Roberta Louise and her oh so sweet soul!!
You are missed Roberta...and you are loved.
Rest In Peace
aqt
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jill
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Post by jill on Jun 5, 2009 7:59:43 GMT -5
Lots of information here to dissect and absorb. I most probably should have started a new thread on the Nanocytes that were 'invented' to keep that subject separate. As you point out, Sky, the scientists that Tam Tam references tell us: oehha.ca.gov/ecotox/Microcystin.htmlExcerpt: However, the effect of the broth was delayed over 3 d in the green algae, Chlorella vulgaris and Scenedesmus sp., and was negligible in a diatom, Navicula sp., indicating the potential for the selective control of cyanobacterial blooms. end excerpt Lots here- to follow up with this scientist: tinyurl.com/p9d3ozFollow the research- Rhinosporidiosis- goes from discovery of the 'Causative agent' -Cyanobacteria to various cancers. * squamous cell carcinoma in the tongue * tumor cell behaviour in human breast carcinomas But I have to wonder why Tam Tam highlights this: Excerpt: Why did previous investigators not find well-defined mitochondria? I am convinced that these mitochondria (7) are from human cells. end jcm.asm.org/cgi/content/full/39/1/413When first reading the above, what came to my mind is that the human cells were present due to the fact that people used the pond to bathe. Now I'm not so sure. AQT, Yes, Roberta will be missed- I have to wonder too- years ago her dog Ayla would love to romp in the water. Roberta posted stories about all of that. Knowing what we now know- did her dog pick up something in the water? Jill
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jill
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Post by jill on Jun 5, 2009 8:55:18 GMT -5
As an aside, notice that L Mendoza, et al, disagrees with the Cyano theory of Dr Ahluwalia, et al. Note that L Mendoza was the scientist that cured the Queens Swans- she had given swans to a park in Florida- will post on that. The Swans- had Rhinosporidiosis. Point- L Mendoza has the cure.... jcm.asm.org/cgi/content/full/39/1/413Scroll down about 1/2 through the above link for Reply to Dr Ahluwalia by Mendoza, et al...
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jill
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Post by jill on Jun 5, 2009 8:57:54 GMT -5
www.thamesweb.co.uk/swans/swan_projectPR03.htmFair use Excerpt: Dr.Mendoza found his picture and an article about his contribution to saving the lives of some of the Queen's swans. The Queen had provided swans to Orange Lake Resort & Country Club in Lakeland Florida several years ago. Dr.Mendoza was consulted when the swans developed what appeared to be a fungal disease. He diagnosed Rhinosporidiosis and appropriate treatment was instituted. The story now appears on the Queen's website. Dr. Mendoza is best known for his unique expertise on a fungal-like organism called Pythium insidiosum that causes lethal infections in horses, dogs, cats and humans. He has developed a treatment , a sort of post-infection vaccine, that is effective in about
70% of infected horses and has some success in other animals as well. The patent on this product, and a pending patent on a latex test for Pythium have been licensed by a start up company that plans to seek USDA approval for the products and to market them to the veterinary community. end I suggest we find the PATENT ?
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Post by aqt on Jun 5, 2009 11:39:42 GMT -5
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Post by aqt on Jun 5, 2009 11:40:16 GMT -5
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jill
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Post by jill on Jun 5, 2009 13:07:15 GMT -5
Hey, good work AQT! At least we know there is a treatment out there....
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Post by aqt on Jun 5, 2009 17:34:03 GMT -5
not sure I would take a vaccine as treatment....I'm sure there is a better way!!!!
aqt ;D
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jill
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Post by jill on Jun 6, 2009 10:38:06 GMT -5
So far, I can't seem to locate the treatment method- L Mendoza- but will keep looking... It can't be the Vaccine, can it? Older Mendoza patents: tinyurl.com/o74vag United States Patent 6,287,573 Mendoza September 11, 2001 Method and vaccine for treatment of Pythiosis insidiosi in humans and lower animals Abstract A method and vaccine for treatment of pythiosis in humans and animals is described. In particular a vaccine comprising a mixture of extracellular and intracellular proteins is described. The vaccine enables cures of chronic pythiosis in some patients. Inventors: Mendoza; Alberto L. (Haslett, MI) Assignee: Board of Trustees operating Michigan State University (East Lansing, MI) Appl. No.: 09/082,232 Filed: May 20, 1998 tinyurl.com/n7ocpyUnited States Patent 5,948,413 Mendoza September 7, 1999 Method and vaccine for treatment of pythiosis insidiosi in humans and lower animals Abstract A method and vaccine for treatment of pythiosis in humans and animals is described. In particular a vaccine comprising a mixture of extracellular and intracellular proteins is described. The vaccine enables cures of chronic pythiosis in some patients. Inventors: Mendoza; Alberto L. (Haslett, MI) Assignee: Board of Trustees operating Michigan State University (East Lansing, MI) Appl. No.: 08/895,940 Filed: July 17, 1997
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jill
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Post by jill on Jun 6, 2009 10:59:08 GMT -5
pythium.pavlab.com/Fair use Pythiosis results from the infection with the fungal-like organism Pythium insidiosum and occurs in Equines, Canines, Felines, Bovines, Humans and other species. This disease is also known as Phycomycosis, “Florida Horse Leeches”, Swamp Cancer and other colloquial names. The disease is worldwide in distribution and is especially prevalent in tropical regions. Recently, numerous cases have been reported in the Midwest and Northeast United States and as far north as Wisconsin and Washington state. Pythium insidiosum is an Oomycete of the Kingdom Stramenopila. Pythium develops hyphae like structures and, in culture, appears similar to the fungi. It is one of many organisms belonging to the Pythium family which typically infect plants in very wet environments. Pythium propagates by producing motile Oospores which travel through standing water and infect new hosts. Oospores which come in contact with susceptible animals may invade via breaks in the skin and set up infection. During the past 10 years, we have studied the Pythium life cycle, introduced several immunological diagnostic assays, and developed an immunotherapeutic product to treat the patient's allergic reaction which is the key to the tissue destruction seen in Pythium infections.
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Post by aqt on Mar 24, 2010 15:55:40 GMT -5
bumpedy bump
aqt
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