Post by skyship on Apr 2, 2010 14:11:52 GMT -5
I do believe the core of Morgellon issues involved
the rearrangement of cellular structure, namely
the cytoskeleton.
Biomineralization would be part of this phenomena.
Biometallization introducing metalloproteins to the structure.
Biocrosslinking to existing neuromuscular structures
Biochemical reactions inside of cells.
Biophysics reaction in charged, heated particles.
In order to redo the structure of the cytoskeleton
system, a new architecture is integrated.
The first studies on muscle fibers was done with
Neospora crassa.
Many institutions were involved in this.
===========================
Synopsis of report and who involved:
Is 251 pages long...... I have original......
It covers blueprint, if read between lines.
Where microbiology and molecular biology
Is a model filamentous fungus
------------
Lessons from the Genome Sequence of Neurospora crassa: Tracing the Path from Genomic Blueprint to Multicellular Organism
We present an analysis of over 1,100 of the ~10,000 predicted proteins encoded by the genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of Neurospora genomics and biology are covered. First, the basic features of the genome, including the automated assembly, gene calls, and global gene analyses are summarized. The second section covers components of the centromere and kinetochore complexes, chromatin assembly and modification, and transcription and translation initiation factors. The third area discusses genome defense mechanisms, including repeat induced point mutation, quelling and meiotic silencing, and DNA repair and recombination. In the fourth section, topics relevant to metabolism and transport include extracellular digestion; membrane transporters; aspects of carbon, sulfur, nitrogen, and lipid metabolism; the mitochondrion and energy metabolism; the proteasome; and protein glycosylation, secretion, and endocytosis. Environmental sensing is the focus of the fifth section with a treatment of two-component systems; GTP-binding proteins; mitogen-activated protein, p21-activated, and germinal center kinases; calcium signaling; protein phosphatases; photobiology; circadian rhythms; and heat shock and stress responses. The sixth area of analysis is growth and development; it encompasses cell wall synthesis, proteins important for hyphal polarity, cytoskeletal components, the cyclin/cyclin-dependent kinase machinery, macroconidiation, meiosis, and the sexual cycle. The seventh section covers topics relevant to animal and plant pathogenesis and human disease. The results demonstrate that a large proportion of Neurospora genes do not have homologues in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. The group of unshared genes includes potential new targets for antifungals as well as loci implicated in human and plant physiology and disease.
mmbr.asm.org/cgi/content/abstract/68/1/1
Indications that more was being contemplated than just
the fungus. Studies comparable to the human genome.
Note what they were studying, and included in that is
the m- inositol..... that was investigated before that.
www.jstor.org/pss/2439649
Scherer in 1850 isolated the "hexahydroxycyclohexane
myo-inositol from muscle.
hexahydroxycyclohexane myo-inositol:
inositol [i′näs·ə‚tȯl]
(organic chemistry)
C6H6(OH)6·2H2O A water-soluble alcohol often grouped with the vitamins; there are nine stereoisomers of hexahydroxycyclohexane, and the only one of biological importance is optically inactivemeso-inositol, comprising white crystals, widely distributed in animals and plants; it serves as a growth factor for animals and microorganisms.
----
Inositol
The generic name for hexahydroxycyclohexanes, which are classified as carbohydrates. The inositols have exceptional chemical stability and are easily crystallized. Of the forms common in nature, the most ubiquitous and biologically important is myoinositol, a water-soluble crystalline compound. Many biological functions require myoinositol, and thus it is identified as an essential metabolite. Although originally classified as a vitamin, myoinositol is now known to be a cellular precursor of phospholipids that serve as a source of metabolic regulators and as membrane anchors for certain proteins. Some microorganisms require exogenous myoinositol for growth. See Carbohydrate, Lipid
encyclopedia2.thefreedictionary.com/1,2,3,4,5,6-hexahydroxycyclohexane
skyship
the rearrangement of cellular structure, namely
the cytoskeleton.
Biomineralization would be part of this phenomena.
Biometallization introducing metalloproteins to the structure.
Biocrosslinking to existing neuromuscular structures
Biochemical reactions inside of cells.
Biophysics reaction in charged, heated particles.
In order to redo the structure of the cytoskeleton
system, a new architecture is integrated.
The first studies on muscle fibers was done with
Neospora crassa.
Many institutions were involved in this.
===========================
Synopsis of report and who involved:
Is 251 pages long...... I have original......
It covers blueprint, if read between lines.
Where microbiology and molecular biology
Is a model filamentous fungus
------------
Lessons from the Genome Sequence of Neurospora crassa: Tracing the Path from Genomic Blueprint to Multicellular Organism
We present an analysis of over 1,100 of the ~10,000 predicted proteins encoded by the genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of Neurospora genomics and biology are covered. First, the basic features of the genome, including the automated assembly, gene calls, and global gene analyses are summarized. The second section covers components of the centromere and kinetochore complexes, chromatin assembly and modification, and transcription and translation initiation factors. The third area discusses genome defense mechanisms, including repeat induced point mutation, quelling and meiotic silencing, and DNA repair and recombination. In the fourth section, topics relevant to metabolism and transport include extracellular digestion; membrane transporters; aspects of carbon, sulfur, nitrogen, and lipid metabolism; the mitochondrion and energy metabolism; the proteasome; and protein glycosylation, secretion, and endocytosis. Environmental sensing is the focus of the fifth section with a treatment of two-component systems; GTP-binding proteins; mitogen-activated protein, p21-activated, and germinal center kinases; calcium signaling; protein phosphatases; photobiology; circadian rhythms; and heat shock and stress responses. The sixth area of analysis is growth and development; it encompasses cell wall synthesis, proteins important for hyphal polarity, cytoskeletal components, the cyclin/cyclin-dependent kinase machinery, macroconidiation, meiosis, and the sexual cycle. The seventh section covers topics relevant to animal and plant pathogenesis and human disease. The results demonstrate that a large proportion of Neurospora genes do not have homologues in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. The group of unshared genes includes potential new targets for antifungals as well as loci implicated in human and plant physiology and disease.
mmbr.asm.org/cgi/content/abstract/68/1/1
Indications that more was being contemplated than just
the fungus. Studies comparable to the human genome.
Note what they were studying, and included in that is
the m- inositol..... that was investigated before that.
www.jstor.org/pss/2439649
Scherer in 1850 isolated the "hexahydroxycyclohexane
myo-inositol from muscle.
hexahydroxycyclohexane myo-inositol:
inositol [i′näs·ə‚tȯl]
(organic chemistry)
C6H6(OH)6·2H2O A water-soluble alcohol often grouped with the vitamins; there are nine stereoisomers of hexahydroxycyclohexane, and the only one of biological importance is optically inactivemeso-inositol, comprising white crystals, widely distributed in animals and plants; it serves as a growth factor for animals and microorganisms.
----
Inositol
The generic name for hexahydroxycyclohexanes, which are classified as carbohydrates. The inositols have exceptional chemical stability and are easily crystallized. Of the forms common in nature, the most ubiquitous and biologically important is myoinositol, a water-soluble crystalline compound. Many biological functions require myoinositol, and thus it is identified as an essential metabolite. Although originally classified as a vitamin, myoinositol is now known to be a cellular precursor of phospholipids that serve as a source of metabolic regulators and as membrane anchors for certain proteins. Some microorganisms require exogenous myoinositol for growth. See Carbohydrate, Lipid
encyclopedia2.thefreedictionary.com/1,2,3,4,5,6-hexahydroxycyclohexane
skyship